INCREMENTAL VALUE OF BIVENTRICULAR STRAIN IN PATIENTS WITH SEVERE AORTIC STENOSIS.

BackgroundLeft ventricular global longitudinal (LVGLS) and right ventricular free wall strain (RVFWS) demonstrated separately prognostic value inpatients with severe aortic...

THE OUT-OF-HOSPITAL CARDIAC ARREST IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND PRE-EXISTING AORTIC STENOSIS.

Pre-existing significant aortic stenosis(sAS) in patients with out-of-hospital cardiac arrest(OHCA) may lead to ineffective chest compressions due to hemodynamic of...

IMPACT OF MITRAL VALVE REPAIR ON REGIONAL AND GLOBAL LV REMODELING IN BARLOW’S DISEASE

Aims: To assess the left ventricular (LV) reverse remodeling 1.5 years after mitral surgery in patients with Barlow's disease. Sample...

EFFECTIVENESS OF CONTEMPORARY RISK STRATIFICATION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY: A PILOT STUDY

Risk stratification and primary prevention of sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM) is a challenging discipline....

PREVALENCE OF TRANSTHYRETIN AMYLOIDOSIS IN PATIENTS WITH SEVERE AORTIC STENOSIS UNDERGOING TRANSCATHETER AORTIC VALVE REPLACEMENT – PRELIMINARY RESULTS OF A PROSPECTIVE STUDY

ContextAortic stenosis (AS) and transthyretin amyloidosis (ATTR) are diseases with increased prevalence at higher age. We report our single centre...

GENETIC BASIS FOR CARDIOMYOPATHY IN A REPRESENTATIVE COHORT IN THE CZECH REPUBLIC

Aim: Inherited cardiomyopathies are an important cause of heart failure in patients < 50 years. Our study aims to assess...

INNATE IMMUNITY AND DOXORUBICIN-CARDIOMYOPATHY.

Rationale: Cytokines such as TNFα have been implicated in cardiac dysfunction and toxicity associated with doxorubicin (DOX). While TNFα can...

THE IMPORTANCE OF SEX DIFFERENCES IN LEFT VENTRICULAR REMODELING FOR RISK STRATIFICATION OF PATIENTS WITH AORTIC REGURGITATION

Background: Left ventricular(LV) dilatation is an established prognosticator in aortic regurgitation(AR). Current guidelines recommend using LV end-systolic diameter index (LVESDi)...

SEX DIFFERENCES IN CARDIAC TOLERANCE TO OXYGEN DEPRIVATION - 40 YEARS OF CARDIOVASCULAR RESEARCH

  Experimental and clinical studies have clearly demonstrated significant sex differences in myocardial structure and function, both under physiological and pathological...

SEX-DIFFERENCES IN TRIGLYCERIDEMIC GENETIC RISK SCORES AND RISK OF MYOCARDIAL INFARCTION.

Aim: Elevated plasma triglyceride (TG) levels are an independent risk factor for the development of cardiovascular disease, including myocardial infarction...

STUDY OF THE EFFECTIVENESS OF MINERALOCORTICOID RECEPTOR ANTAGONISTS ON NEUROHUMORAL PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE

Aim. To study the effectiveness of mineralocorticoid receptor antagonists-spirinolactone and eplerenone on neurohumoral parameters in patients with chronic heart failure...

ANALYSIS OF IRON DEFICIENCY IN DIABETIC AND NON-DIABETIC PATIENTS WITH HEART FAILURE

Introduction: Iron deficiency (ID) is a common comorbidity in patients with heart failure (HF) and has been associated with decreased...

EICOSANOIDS IN CORONARY SINUS NEGATIVELY CORRELATE WITH NATRIURETIC PEPTIDES IN HEART FAILURE WITH REDUCED EJECTION FRACTION: INSIGHTS FROM EICOSANOIDS IN HUMAN HEART FAILURE STUDY

Background: The diagnostic and therapeutic potential of eicosanoids, metabolites of arachidonic acid with positive cardio-renal activity in preclinical heart failure...

AN ASSOCIATION OF BIOMARKERS OF CARDIAC REMODELING, MYOCARDIAL FIBROSIS AND INFLAMMATION WITH THE PARAMETERS OF HEART FUNCTION AND STRUCTURE IN THE PATIENTS WITH ARTERIAL HYPERTENSION

Backround: An early evaluation of the cardiac remodeling may be usefull in the prediction of heart failure development in the...

SPINAL CORD STIMULATION IN THE TREATMENT OF REFRACTORY ANGINA PECTORIS: 25-YEAR CLINICAL EXPERIENCE AT A SINGLE CENTER

Background: The efficacy of spinal cord stimulation (SCS) in refractory angina pectoris (RAP) has been proven by several smaller randomized...

IRON DEFICIENCY AND ALL-CAUSE MORTALITY AFTER MYOCARDIAL INFARCTION

IntroductionIron deficiency (ID) is a common comorbidity of cardiovascular diseases, including myocardial infarction (MI). However, the data on the clinical...

MYOCARDIAL INFARCTION WITH MULTIVESSEL DISEASE. DOES PRESENCE OF CHRONIC TOTAL OCCLUSION MAKES A DIFFERENCE?

Aim:To analyze clinical characteristics, presenting symptoms, and survival of patients with myocardial infarction (MI), multivessel disease (MVD), and the possible...

PRETREATMENT WITH DUAL ANTIPLATELET THERAPY IN ACUTE MYOCARDIAL INFARCTION

Background. Combined antithrombotic therapy prevents thrombus progression and its components embolization, and thus, it has an essential role in coronary...

THE HEMODYNAMIC EFFECTS OF SILVER NANOPARTICLES IN A SEPTIC PORCINE MODEL.

Introduction: Infectious diseases, which frequently lead to life-threatening sepsis and septic shock, represent a significant global health challenge. The pursuit...

THE TIME-DEPENDENT YIELD OF INVASIVE VS. STANDARD RESUSCITATION STRATEGIES: A SECONDARY ANALYSIS OF THE PRAGUE OUT-OF-HOSPITAL CARDIAC ARREST STUDY

Background: It is unclear how invasive resuscitative protocols may impact the time-dependent prognosis of out-of-hospital cardiac arrest (OHCA) resuscitations, or...

CARDIAC RHYTHM CONVERSIONS AND THE OUTCOME IN REFRACTORY OUT-OF-HOSPITAL CARDIAC ARREST. COMPARISON OF EXTRACORPOREAL VS. CONVENTIONAL CARDIOPULMONARY RESUSCITATION.

Background: Whether cardiac rhythm conversions during cardiopulmonary resuscitation (CPR) in refractory out-of hospital cardiac arrest (OHCA) affect outcome is not...

OPTIMISING VENOARTERIAL ECMO CARE: INSIGHTS FROM A CARDIAC CENTRE WITHOUT ON-SITE CARDIOSURGICAL EXPERTISE.

Introduction: This study evaluates the safety and efficacy of VA-ECMO in a cardiology center without on-site cardiac surgery, focusing on...

EXTRACORPOREAL MEMBRANE OXYGENATION IN THE THERAPY OF CARDIOGENIC SHOCK: ONE-YEAR OUTCOMES OF THE MULTICENTER, RANDOMIZED ECMO-CS TRIAL

Background and aims: Among patients with cardiogenic shock, immediate initiation of extracorporeal membrane oxygenation (ECMO) did not demonstrate any benefit...

PULSED FIELD ABLATION INDUCES HEMOLYSIS IN VITRO DEPENDING ON THE STRENGTH OF THE ELECTRIC FIELD

Aim:Several cases of renal failure due to intravascular hemolysis after pulsed field ablation (PFA) has been observed. Red blood cell...

THE IMPORTANCE OF THE SCAR BORDER ZONE FOR CHARACTERISTICS OF VENTRICULAR TACHYCARDIA AND ABLATION OUTCOME IN POST MYOCARDIAL INFARCTION PATIENTS

Introduction: Post-myocardial infarction (MI) ventricular tachycardias (VT) are typically related to fixed conduction block in transmural or sub-endocardial scars. However,...

GENOTYPE, PHENOTYPE AND OUTCOMES OF PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY REFERRED FOR ABLATION OF VENTRICULAR TACHYCARDIA.

Background:Sustained monomorphic ventricular tachycardia (SMVT) is the most common ventricular arrhythmia (VA) subtype in hypertrophic cardiomyopathy (HCM) patients with ICD....

INHERITED LONG QT SYNDROME – RECENT ADVANCES

Long QT Syndrome (LQTS) is one of the inherited arrhythmic conditions, where affected individuals may be asymptomatic or may present...

INFLAMMATORY PATHWAYS ARE INVOLVED IN THE DEVELOPMENT OF PULMONARY VASCULOPATHY IN HEART FAILURE: TRANSPULMONARY PROTEOMICS STUDY

Background: Some, but not all, patients with heart failure (HF) develop pulmonary vascular disease (PVD), which contributes to poor prognosis. Mechanisms...

LEFT ATRIAL STRAIN INDEX IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION

Background. In patients with heart failure with preserved ejection fraction(HFpEF), assessment of left ventricular end-diastolic pressure (LVEDP) is crucial but...

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