IMPACT OF MITRAL VALVE REPAIR ON REGIONAL AND GLOBAL LV REMODELING IN BARLOW’S DISEASE

Aims: To assess the left ventricular (LV) reverse remodeling 1.5 years after mitral surgery in patients with Barlow's disease. Sample and methodology: Patients with Barlow’s disease referred for mitral surgery were recruited prospectively at one Heart Valve Clinic between 2017-2022. LV size was evaluated in 2D by the end diastolic (LVIDd) and end-systolic (LVIDs) diameters, and in 3D by the end-diastolic (EDV) and end-systolic (ESV) volumes. LV global function was evaluated by 3D ejection fraction (EF) and 2D global longitudinal strain (GLS). Postoperative changes in regional LV function were assessed by the ratio of basal, middle and apical longitudinal speckle-tracking strain, to global LV GLS. Results: 20 patients with median follow-up time 16 months. All patients were operated with mitral valve repair with annuloplasty and implantation of neo-chordae. Ventricularisation of disjunction was done in all patients with mitral annular disjunction (MAD), while leaflet resection was performed in 65 % of patients. 2D LV end-diastolic and end-systolic diameters were reduced after surgery (6.0±0.6 to 5.4±0.6, p