IDENTIFICATION A NOVEL MUTATION OF TROPONIN-T GENE CAUSING MALIGNANT FORM OF HYPERTROPHIC CARDIOMYOPATHY
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Type: Presentation - doctors , Number in the programme: 21 | |
Losonczi L.1, Kádár K.2, Sepp R.3, Németh K.1, Földesi C.2, Csanády M.3, Fekete G.1 1 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary, 2 Gottsegen György Hungarian Institute of Cardiology, Budapest, Hungary, 3 Department of Internal Medicine and Cardiology Center, Faculty of Medicine, University of Szeged, Szeged, Hungary | |
Objectives: Genetic origin is important in the development of hypertrophic cardiomyopathy (HCM) which is characterized by myocardial hypertrophy and rhythm disorders. The third most common mutated gene leading to HCM is the troponin-T (TNNT2) gene with an incidence of 2%. Our aim was to analyze mutations of the TNNT2 gene in children and young adults. | |