PREDICTORS OF ELECTRICAL DYSSYNCHRONY WITH RIGHT VENTRICULAR APICAL PACING
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Type: Presentation - doctors , Number in the programme: 42 | |
Chadaide S.1, Pap R.1, Attila M.1, Gabor B.1, Laszlo S.1 1 Cardiology, University of Szeged, Szeged, Hungary | |
Background. Left ventricular (LV) electrical dyssynchrony reflected by prolonged paced QRS duration is a predictor of development of heart failure during right ventricular apical (RVA) pacing. Results. Patients had normal to poor LV function (ejection fraction range: 20-75 %) and a variable degree of His-Purkinje system disease (HV interval range: 40-153 ms). Left ventricular ejection fraction (EF), end-systolic diameter and HV interval correlated with both native and paced QRS duration (R= -0.64, 0.62, 0.36 and -0.52, 0.48, 0.28 respectively, p<0.05). With multiple stepwise regression analysis only native QRS duration was identified as an independent predictor of paced QRS width (R=0.73, p<0.001). In patients with normal systolic LV function (EF>50%, n=34) only HV interval correlated with native QRS duration (R=0.38, p=0.013), which in turn predicted paced QRS width (R=0.37, p=0.016). In patients with reduced EF (n=16) LV dimensions and HV interval both correlated with native QRS duration (R=0.57, 0.47 and 0.48, respectively, p<0.05). With stepwise regression HV interval and native QRS width were identified as independent predictors of paced QRS duration (R=0.72 and 0.74, respectively, p<0.01). | |